Chapters 1 to 8

1: Setting the Scene

Multicellular life—mitochondria—glucose—oxygen—ATP—atmospheric pressure—gravity—space suits—weather systems—altitude—Henry's law—breathing—free radicals—cytochrome oxidase—compressed air treatment—conception—hypoxia-inducible factor proteins—blood flow—the heart—Mount Everest—aircraft—inflammation

2: The Brain: The Ultimate Oxygen Machine


Plants—the sun—lungs—Dalton's law—haemoglobin—plasma—Everest—nitric oxide—blood-brain barrier—cerebro-spinal fluid—veins—glucose—GLUT proteins—myelin sheaths—surfactants—insulation—hemispheres—basal ganglia—brain stem—cerebellum—spinal cord—Circle of Willis—anastomoses—lenticulostriate arteries—ischaemic penumbra—reperfusion injury—hyperbaric oxygen treatment

3: The Importance of Pressure and Oxygen


Balloons—altitude hypoxia—unconsciousness—Everest—atmosphericpressure—free radicals—diving—flying—cabin pressurisation—birds—dinosaurs—aircraft—DVT—Paul Bert—genes

4: John Scott Haldane: A Giant of Medicine


John Scott Haldane—Vikings—Gleneagles—Edinburgh—Copley Medal—George Bruce—James "Paraffin" Young—shaleBP—Dundee—London—mining—carbon monoxide—canaries—hypoxia—Pike's Peak—mountain sickness—carbon dioxide—hyperventilation—tetany—COPD—oxygen treatment

5: Oxygen Treatment: When Air is Not Enough


WW1—chlorine—Ypres—Haldane—lung inflammation—oxygen apparatus—masks—oxygen treatment—lung surfactant—pulmonary oedema—pneumonia—Don Valenzuela—Comroe—oxygen breathing—diving—atelectasis—CD40-CD40—neutrophils—free radicals—ventilator lung damage

6: Taking to the Air


Zeppelins—Wright brothers—WW1—altitude hypoxia—oxygen apparatus—supercharging—fatigue—brain swelling—Everest—pressure cabins—B29—nuclear war—Comet—Concorde—free radicals—scavengers—nitric oxide—HIF 1 alpha—decompression—bubbles—decompression sickness—Frank Whittle—gas turbines—jet aircraft—decompression sickness—treatment—diving

7: Bubbles, the "Bends," and the Lungs


Diving—bubbles—the bends—micro-embolism— Semmelweis—syphilis—malaria—Artemisinin—the lung filter—gas—MRI—brain—spinal cord—blood-brain barrier—neutrophils—hyperbaric oxygen treatment

8: Oxygen: Diving, Flying, and Medicine


Oxygen diving—military pilots—toxicity—nitric oxide—vasoconstriction—retina—lung tears—bubbles—hyperbaric pressures—compressed-airworkers—amateur divers—oxygen recompression treatment—blood-brain barrier—spinal cord—paraplegia—hyperbaric oxygen treatment—neutrophils